Anastrozole tablet is a medication commonly used to prevent and treat certain types of cancer in postmenopausal women, including breast and ovarian cancer. A recent study has looked into the potential for Anastrozole tablets to influence cognitive function, exploring the pattern of change in a cognitive function used when taking the drug.
Results from the research study
The study found that Anastrozole 1mg Tablet use in postmenopausal women causes a decline in cognitive function that lasts up to a year after the drug is used. This decline specifically affects the Verbal Memory Domain and Maths Component Composite scores, although no decline in Visual Memory Domain scores was observed. The decline in these Verbal and Maths scores is believed to be due to anastrozole’s effect on the hypothalamic-pituitary-gonadal (HPG) axis. The HPG axis helps to regulate both cognitive function and estrogen levels, and anastrozole’s effects on this axis could explain the decline of cognitive function observed in the study.
Anastrozole effect on brain function
As time passes, the participants’ verbal and maths scores slowly begin to improve again. However, the verbal scores never fully recover to the level before Anastrozole 1 mg tablet was taken and there is some evidence that cognitive decline persists even over two and a half years. The study did not report any improvement in the visual memory scores, suggesting that Anastrozole does not affect visual memory efficiency.
The pattern of cognitive decline observed over a period of time
The pattern of decline in cognitive function from taking Anastrozole appears to have a particular shape. The performance begins to decline upon the first six months of taking the drug with the decline stabilizing for the next six months before slow improvements begin to be made by the end of the second year. It is important to note that the exact pattern of decline and improvement may vary from person to person and should not be assumed to apply to all individuals taking the drug.
The cost of a one-month supply of Anastrozole tablet depends on whether the medication is purchased through a regular or specialty pharmacy. When purchased through a regular pharmacy, one month of Anastrozole can cost anywhere from a specific range. Prices vary based on the size of the dosage, brand name, quantity, and pharmacy prices.
In conclusion, Anastrozole can cause a decline in cognitive function in postmenopausal women that lasts up to a year, with a continuing decline persisting even two and a half years afterwards. In particular, scores on the Verbal Memory Domain and Maths Component Composite are affected, displaying a pattern of initial decline, plateau and then slow improvement over time. It is important for healthcare professionals to be aware of the potential effects of Anastrozole on cognitive function and to monitor their patients for any changes.